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Development of polycationic amphiphilic cyclodextrin nanoparticles for anticancer drug delivery

Background: Paclitaxel is a potent anticancer drug that is effective against a wide spectrum of cancers. To overcome its bioavailability problems arising from very poor aqueous solubility and tendency to recrystallize upon dilution, paclitaxel is commercially formulated with co-solvents such as Crem...

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Detalles Bibliográficos
Autores principales: Varan, Gamze, Benito, Juan M, Mellet, Carmen Ortiz, Bilensoy, Erem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530618/
https://www.ncbi.nlm.nih.gov/pubmed/28900599
http://dx.doi.org/10.3762/bjnano.8.145