Cargando…

Perioperative management of patients with severe hypophosphataemia secondary to oncogenic osteomalacia: Our experience and review of literature

Oncogenic osteomalacia (OOM) is a rare paraneoplastic syndrome associated with mesenchymal tumours. It is characterised by phosphaturia, hypophosphataemia, decreased serum Vitamin D3 levels and severe osteomalacia. OOM-inducing tumours are usually benign, arising either from bone or soft tissue, wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Verma, Alka, Tewari, Saipriya, Kannaujia, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530746/
https://www.ncbi.nlm.nih.gov/pubmed/28794533
http://dx.doi.org/10.4103/ija.IJA_57_17
_version_ 1783253306040123392
author Verma, Alka
Tewari, Saipriya
Kannaujia, Ashish
author_facet Verma, Alka
Tewari, Saipriya
Kannaujia, Ashish
author_sort Verma, Alka
collection PubMed
description Oncogenic osteomalacia (OOM) is a rare paraneoplastic syndrome associated with mesenchymal tumours. It is characterised by phosphaturia, hypophosphataemia, decreased serum Vitamin D3 levels and severe osteomalacia. OOM-inducing tumours are usually benign, arising either from bone or soft tissue, with extremities and craniofacial region being the most common sites. Surgical resection of the tumour remains the mainstay of treatment. Challenges to an anaesthesiologist arise when such patients are planned for surgical resection of the underlying tumour. All the perioperative dilemmas are directly related to the severe hypophosphataemia. We describe three such cases of OOM and their perioperative management.
format Online
Article
Text
id pubmed-5530746
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-55307462017-08-09 Perioperative management of patients with severe hypophosphataemia secondary to oncogenic osteomalacia: Our experience and review of literature Verma, Alka Tewari, Saipriya Kannaujia, Ashish Indian J Anaesth Case Report Oncogenic osteomalacia (OOM) is a rare paraneoplastic syndrome associated with mesenchymal tumours. It is characterised by phosphaturia, hypophosphataemia, decreased serum Vitamin D3 levels and severe osteomalacia. OOM-inducing tumours are usually benign, arising either from bone or soft tissue, with extremities and craniofacial region being the most common sites. Surgical resection of the tumour remains the mainstay of treatment. Challenges to an anaesthesiologist arise when such patients are planned for surgical resection of the underlying tumour. All the perioperative dilemmas are directly related to the severe hypophosphataemia. We describe three such cases of OOM and their perioperative management. Medknow Publications & Media Pvt Ltd 2017-07 /pmc/articles/PMC5530746/ /pubmed/28794533 http://dx.doi.org/10.4103/ija.IJA_57_17 Text en Copyright: © 2017 Indian Journal of Anaesthesia http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Verma, Alka
Tewari, Saipriya
Kannaujia, Ashish
Perioperative management of patients with severe hypophosphataemia secondary to oncogenic osteomalacia: Our experience and review of literature
title Perioperative management of patients with severe hypophosphataemia secondary to oncogenic osteomalacia: Our experience and review of literature
title_full Perioperative management of patients with severe hypophosphataemia secondary to oncogenic osteomalacia: Our experience and review of literature
title_fullStr Perioperative management of patients with severe hypophosphataemia secondary to oncogenic osteomalacia: Our experience and review of literature
title_full_unstemmed Perioperative management of patients with severe hypophosphataemia secondary to oncogenic osteomalacia: Our experience and review of literature
title_short Perioperative management of patients with severe hypophosphataemia secondary to oncogenic osteomalacia: Our experience and review of literature
title_sort perioperative management of patients with severe hypophosphataemia secondary to oncogenic osteomalacia: our experience and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530746/
https://www.ncbi.nlm.nih.gov/pubmed/28794533
http://dx.doi.org/10.4103/ija.IJA_57_17
work_keys_str_mv AT vermaalka perioperativemanagementofpatientswithseverehypophosphataemiasecondarytooncogenicosteomalaciaourexperienceandreviewofliterature
AT tewarisaipriya perioperativemanagementofpatientswithseverehypophosphataemiasecondarytooncogenicosteomalaciaourexperienceandreviewofliterature
AT kannaujiaashish perioperativemanagementofpatientswithseverehypophosphataemiasecondarytooncogenicosteomalaciaourexperienceandreviewofliterature