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Oligomeric amyloid-beta induces MAPK-mediated activation of brain cytosolic and calcium-independent phospholipase A(2) in a spatial-specific manner
Alzheimer’s disease (AD) is histopathologically characterized by the build-up of fibrillar amyloid beta (Aβ) in the form of amyloid plaques and the development of intraneuronal neurofibrillary tangles consisting of aggregated hyperphosphorylated Tau. Although amyloid fibrils were originally consider...
Autores principales: | Palavicini, Juan Pablo, Wang, Chunyan, Chen, Linyuan, Hosang, Kristen, Wang, Jianing, Tomiyama, Takami, Mori, Hiroshi, Han, Xianlin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530945/ https://www.ncbi.nlm.nih.gov/pubmed/28750656 http://dx.doi.org/10.1186/s40478-017-0460-6 |
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