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Extracellular vesicles from human liver stem cells restore argininosuccinate synthase deficiency

BACKGROUND: Argininosuccinate synthase (ASS)1 is a urea cycle enzyme that catalyzes the conversion of citrulline and aspartate to argininosuccinate. Mutations in the ASS1 gene cause citrullinemia type I, a rare autosomal recessive disorder characterized by neonatal hyperammonemia, elevated citrullin...

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Detalles Bibliográficos
Autores principales:	Herrera Sanchez, Maria Beatriz, Previdi, Sara, Bruno, Stefania, Fonsato, Valentina, Deregibus, Maria Chiara, Kholia, Sharad, Petrillo, Sara, Tolosano, Emanuela, Critelli, Rossana, Spada, Marco, Romagnoli, Renato, Salizzoni, Mauro, Tetta, Ciro, Camussi, Giovanni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531104/ https://www.ncbi.nlm.nih.gov/pubmed/28750687 http://dx.doi.org/10.1186/s13287-017-0628-9

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