Reversal of murine alcoholic steatohepatitis by pepducin-based functional blockade of interleukin-8 receptors

OBJECTIVE: Alcoholic steatohepatitis is a life-threatening condition with short-term mortality up to 40%. It features hepatic neutrophil infiltration and blood neutrophilia, and may evolve from ethanol-induced breakdown of the enteric barrier and consequent bacteraemia. Signalling through CXCR1/2 G-...

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Detalles Bibliográficos
Autores principales: Wieser, Verena, Adolph, Timon E, Enrich, Barbara, Kuliopulos, Athan, Kaser, Arthur, Tilg, Herbert, Kaneider, Nicole C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531226/
https://www.ncbi.nlm.nih.gov/pubmed/26858343
http://dx.doi.org/10.1136/gutjnl-2015-310344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531226/
https://www.ncbi.nlm.nih.gov/pubmed/26858343
http://dx.doi.org/10.1136/gutjnl-2015-310344

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