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A single nucleotide polymorphism causes enhanced radical oxygen species production by human aldehyde oxidase
Aldehyde oxidases (AOXs) are molybdo-flavoenzymes characterized by broad substrate specificity, oxidizing aromatic/aliphatic aldehydes into the corresponding carboxylic acids and hydroxylating various heteroaromatic rings. The enzymes use oxygen as the terminal electron acceptor and produce reduced...
Autores principales: | Foti, Alessandro, Dorendorf, Frank, Leimkühler, Silke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531472/ https://www.ncbi.nlm.nih.gov/pubmed/28750088 http://dx.doi.org/10.1371/journal.pone.0182061 |
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