Modified human glucagon-like peptide-1 (GLP-1) produced in E. coli has a long-acting therapeutic effect in type 2 diabetic mice

Glucagon-like peptide 1 (GLP-1) is a very potent insulinotropic hormone secreted into the blood stream after eating. Thus, it has potential to be used in therapeutic treatment of diabetes. The half-life of GLP-1, however, is very short due to its rapid cleavage by dipeptidyl peptidase IV (DPP-IV). T...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Fangfang, Wang, Kevin Yueju, Wang, Nan, Li, Gangqiang, Liu, Dehu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531477/
https://www.ncbi.nlm.nih.gov/pubmed/28750064
http://dx.doi.org/10.1371/journal.pone.0181939

Ejemplares similares

Ejemplares similares