Clinical impact of a targeted next-generation sequencing gene panel for autoinflammation and vasculitis

BACKGROUND: Monogenic autoinflammatory diseases (AID) are a rapidly expanding group of genetically diverse but phenotypically overlapping systemic inflammatory disorders associated with dysregulated innate immunity. They cause significant morbidity, mortality and economic burden. Here, we aimed to d...

Descripción completa

Detalles Bibliográficos
Autores principales: Omoyinmi, Ebun, Standing, Ariane, Keylock, Annette, Price-Kuehne, Fiona, Melo Gomes, Sonia, Rowczenio, Dorota, Nanthapisal, Sira, Cullup, Thomas, Nyanhete, Rodney, Ashton, Emma, Murphy, Claire, Clarke, Megan, Ahlfors, Helena, Jenkins, Lucy, Gilmour, Kimberly, Eleftheriou, Despina, Lachmann, Helen J., Hawkins, Philip N., Klein, Nigel, Brogan, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531484/
https://www.ncbi.nlm.nih.gov/pubmed/28750028
http://dx.doi.org/10.1371/journal.pone.0181874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531484/
https://www.ncbi.nlm.nih.gov/pubmed/28750028
http://dx.doi.org/10.1371/journal.pone.0181874

Ejemplares similares