Cargando…
High levels of adherence to a rectal microbicide gel and to oral Pre-Exposure Prophylaxis (PrEP) achieved in MTN-017 among men who have sex with men (MSM) and transgender women
Trials to assess microbicide safety require strict adherence to prescribed regimens. If adherence is suboptimal, safety cannot be adequately assessed. MTN-017 was a phase 2, randomized sequence, open-label, expanded safety and acceptability crossover study comparing 1) daily oral emtricitabine/tenof...
Autores principales: | Carballo-Diéguez, Alex, Balán, Ivan C., Brown, William, Giguere, Rebecca, Dolezal, Curtis, Leu, Cheng-Shiun, Marzinke, Mark A., Hendrix, Craig W., Piper, Jeanna M., Richardson, Barbra A., Grossman, Cynthia, Johnson, Sherri, Gomez, Kailazarid, Horn, Stephanie, Kunjara Na Ayudhya, Ratiya Pamela, Patterson, Karen, Jacobson, Cindy, Bekker, Linda-Gail, Chariyalertsak, Suwat, Chitwarakorn, Anupong, Gonzales, Pedro, Holtz, Timothy H., Liu, Albert, Mayer, Kenneth H., Zorrilla, Carmen, Lama, Javier, McGowan, Ian, Cranston, Ross D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531503/ https://www.ncbi.nlm.nih.gov/pubmed/28750059 http://dx.doi.org/10.1371/journal.pone.0181607 |
Ejemplares similares
-
A Phase 1 Randomized, Double Blind, Placebo Controlled Rectal Safety and Acceptability Study of Tenofovir 1% Gel (MTN-007)
por: Mcgowan, Ian, et al.
Publicado: (2013) -
Interactive Voice Response System: Data Considerations and Lessons Learned During a Rectal Microbicide Placebo Adherence Trial for Young Men Who Have Sex With Men
por: Bauermeister, Jose, et al.
Publicado: (2017) -
Divergent adherence estimates with pharmacokinetic and behavioural measures in the MTN-003 (VOICE) study
por: van der Straten, Ariane, et al.
Publicado: (2016) -
A randomized trial of safety, acceptability and adherence of three rectal microbicide placebo formulations among young sexual and gender minorities who engage in receptive anal intercourse (MTN-035)
por: Bauermeister, Jose A., et al.
Publicado: (2023) -
Project Gel a Randomized Rectal Microbicide Safety and Acceptability Study in Young Men and Transgender Women
por: McGowan, Ian, et al.
Publicado: (2016)