Roles of the low density lipoprotein receptor and related receptors in inhibition of lipoprotein(a) internalization by proprotein convertase subtilisin/kexin type 9

Elevated plasma concentrations of lipoprotein(a) (Lp(a)) are a causal risk factor for cardiovascular disease. The mechanisms underlying Lp(a) clearance from plasma remain unclear, which is an obvious barrier to the development of therapies to specifically lower levels of this lipoprotein. Recently,...

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Detalles Bibliográficos
Autores principales: Romagnuolo, Rocco, Scipione, Corey A., Marcovina, Santica M., Gemin, Matthew, Seidah, Nabil G., Boffa, Michael B., Koschinsky, Marlys L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531514/
https://www.ncbi.nlm.nih.gov/pubmed/28750079
http://dx.doi.org/10.1371/journal.pone.0180869

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