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Assisted Design of Antibody and Protein Therapeutics (ADAPT)
Effective biologic therapeutics require binding affinities that are fine-tuned to their disease-related molecular target. The ADAPT (Assisted Design of Antibody and Protein Therapeutics) platform aids in the selection of mutants that improve/modulate the affinity of antibodies and other biologics. I...
Autores principales: | Vivcharuk, Victor, Baardsnes, Jason, Deprez, Christophe, Sulea, Traian, Jaramillo, Maria, Corbeil, Christopher R., Mullick, Alaka, Magoon, Joanne, Marcil, Anne, Durocher, Yves, O’Connor-McCourt, Maureen D., Purisima, Enrico O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531539/ https://www.ncbi.nlm.nih.gov/pubmed/28750054 http://dx.doi.org/10.1371/journal.pone.0181490 |
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