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The miR-23a~27a~24-2 microRNA cluster buffers transcription and signaling pathways during hematopoiesis

MicroRNA cluster mirn23a has previously been shown to promote myeloid development at the expense of lymphoid development in overexpression and knockout mouse models. This polarization is observed early in hematopoietic development, with an increase in common lymphoid progenitors (CLPs) and a decreas...

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Detalles Bibliográficos
Autores principales:	Kurkewich, Jeffrey L., Hansen, Justin, Klopfenstein, Nathan, Zhang, Helen, Wood, Christian, Boucher, Austin, Hickman, Joseph, Muench, David E., Grimes, H. Leighton, Dahl, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531666/ https://www.ncbi.nlm.nih.gov/pubmed/28704388 http://dx.doi.org/10.1371/journal.pgen.1006887

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