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Helicobacter pylori modulates host cell responses by CagT4SS-dependent translocation of an intermediate metabolite of LPS inner core heptose biosynthesis

Highly virulent Helicobacter pylori cause proinflammatory signaling inducing the transcriptional activation and secretion of cytokines such as IL-8 in epithelial cells. Responsible in part for this signaling is the cag pathogenicity island (cagPAI) that codetermines the risk for pathological sequela...

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Detalles Bibliográficos
Autores principales:	Stein, Saskia C., Faber, Eugenia, Bats, Simon H., Murillo, Tatiana, Speidel, Yvonne, Coombs, Nina, Josenhans, Christine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531669/ https://www.ncbi.nlm.nih.gov/pubmed/28715499 http://dx.doi.org/10.1371/journal.ppat.1006514

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