Cargando…

Host genetics play a critical role in controlling CD8 T cell function and lethal immunopathology during chronic viral infection

Effective CD8 T cell responses are vital for the control of chronic viral infections. Many factors of the host immune response contribute to the maintenance of effector CD8 T cell responses versus CD8 T cell exhaustion during chronic infection. Specific MHC alleles and the degree of MHC heterogeneit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Christiaansen, Allison F., Schmidt, Megan E., Hartwig, Stacey M., Varga, Steven M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531689/ https://www.ncbi.nlm.nih.gov/pubmed/28715493 http://dx.doi.org/10.1371/journal.ppat.1006498

Ejemplares similares

Memory CD8 T cells mediate severe immunopathology following respiratory syncytial virus infection
por: Schmidt, Megan E., et al.
Publicado: (2018)

Pre-existing neutralizing antibodies prevent CD8 T cell-mediated immunopathology following respiratory syncytial virus infection
por: Schmidt, Megan E., et al.
Publicado: (2019)

Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study
por: Schurink, Bernadette, et al.
Publicado: (2020)

The Double Game Played by Th17 Cells in Infection: Host Defense and Immunopathology
por: Paroli, Marino, et al.
Publicado: (2022)

Viral and Bacterial Infections Interfere with Peripheral Tolerance Induction and Activate CD8(+) T Cells to Cause Immunopathology
por: Ehl, Stephan, et al.
Publicado: (1998)

CD4(+) T cells are trigger and target of the glucocorticoid response that prevents lethal immunopathology in toxoplasma infection
por: Kugler, David G., et al.
Publicado: (2013)

The CD8 T Cell Response to Respiratory Virus Infections
por: Schmidt, Megan E., et al.
Publicado: (2018)

The immunopathology of systemic sclerosis
por: van Laar, Jacob M., et al.
Publicado: (2015)

Cytokines and CD8 T cell immunity during respiratory syncytial virus infection
por: Schmidt, Megan E., et al.
Publicado: (2020)

Antagonistic Variant Virus Prevents Wild-type Virus-induced Lethal Immunopathology
por: Hunziker, Lukas, et al.
Publicado: (2002)

Effector CD8(+) T cell-derived interleukin-10 enhances acute liver immunopathology
por: Fioravanti, Jessica, et al.
Publicado: (2017)

A Critical Role for OX40 in T Cell–mediated Immunopathology during Lung Viral Infection
por: Humphreys, Ian R., et al.
Publicado: (2003)

Viruses and Immunity: Toward Understanding Viral Immunology and Immunopathology
por: Armstrong, Martine Y. K.
Publicado: (1976)

Platelets in Immune Response to Virus and Immunopathology of Viral Infections
por: Hottz, Eugenio D., et al.
Publicado: (2018)

RSV Vaccine-Enhanced Disease Is Orchestrated by the Combined Actions of Distinct CD4 T Cell Subsets
por: Knudson, Cory J., et al.
Publicado: (2015)

“Small” Intestinal Immunopathology Plays a “Big” Role in Lethal Cytokine Release Syndrome, and Its Modulation by Interferon-γ, IL-17A, and a Janus Kinase Inhibitor
por: Kale, Shiv D., et al.
Publicado: (2020)

A gammaherpesvirus-secreted activator of Vβ4(+) CD8(+) T cells regulates chronic infection and immunopathology
por: Evans, Andrew G., et al.
Publicado: (2008)

Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology
por: David, Paul, et al.
Publicado: (2020)

Sirolimus alters lung pathology and viral load following influenza A virus infection
por: Alsuwaidi, Ahmed R., et al.
Publicado: (2017)

Clonal Exhaustion as a Mechanism to Protect Against Severe Immunopathology and Death from an Overwhelming CD8 T Cell Response
por: Cornberg, Markus, et al.
Publicado: (2013)

CCL5 Release by CCR9+ CD8 T Cells: A Potential Contributor to Immunopathology of Primary Sjögren’s Syndrome
por: Hinrichs, Anneline C., et al.
Publicado: (2022)

Mucosal Resident Memory CD4 T Cells in Protection and Immunopathology
por: Turner, Damian Lanz, et al.
Publicado: (2014)

Editorial: Immunopathology of Chronic Bacterial and Viral Diseases Prevalent in Latin America
por: Pelayo, Rosana, et al.
Publicado: (2020)

COPD immunopathology
por: Caramori, Gaetano, et al.
Publicado: (2016)

MicroRNAs in the Host-Apicomplexan Parasites Interactions: A Review of Immunopathological Aspects
por: Judice, Carla C., et al.
Publicado: (2016)

CD226 and TIGIT Cooperate in the Differentiation and Maturation of Human Tfh Cells
por: Yasutomi, Motoko, et al.
Publicado: (2022)

Mutual Interplay of Host Immune System and Gut Microbiota in the Immunopathology of Atherosclerosis
por: Yeh, Chih-Fan, et al.
Publicado: (2020)

Protective function and durability of mouse lymph node-resident memory CD8(+) T cells
por: Anthony, Scott M, et al.
Publicado: (2021)

Immunopathology of angioimmunoblastic lymphadenopathy.
por: Jones, D. B., et al.
Publicado: (1978)

Editorial: Immunopathology of Type 1 Diabetes
por: Green, E. Allison, et al.
Publicado: (2022)

A Numerically Subdominant CD8 T Cell Response to Matrix Protein of Respiratory Syncytial Virus Controls Infection with Limited Immunopathology
por: Liu, Jie, et al.
Publicado: (2016)

NLRP6 Plays an Important Role in Early Hepatic Immunopathology Caused by Schistosoma mansoni Infection
por: Sanches, Rodrigo C. O., et al.
Publicado: (2020)

STING, a critical contributor to SARS-CoV-2 immunopathology
por: Li, Heyu, et al.
Publicado: (2022)

HVEM and CD160: Regulators of Immunopathology During Malaria Blood-Stage
por: Muscate, Franziska, et al.
Publicado: (2018)

CD8(+) T Cells: Exacting a Toll in Viral Pneumonia
por: Ballinger, Megan N., et al.
Publicado: (2020)

Kupffer Cells Hasten Resolution of Liver Immunopathology in Mouse Models of Viral Hepatitis
por: Sitia, Giovanni, et al.
Publicado: (2011)

Type I interferon regulates proteolysis by macrophages to prevent immunopathology following viral infection
por: Lee, Amanda J., et al.
Publicado: (2022)

Introduction: Organ Specific Immunopathology
por: Gershwin, M. Eric, et al.
Publicado: (2004)

The host immune response in respiratory virus infection: balancing virus clearance and immunopathology
por: Newton, Amy H., et al.
Publicado: (2016)

TREATMENT WITH SOLUBLE CD24 ATTENUATES COVID-19-ASSOCIATED SYSTEMIC IMMUNOPATHOLOGY
por: Song, No-Joon, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qposegjd2f0fm1bljltu836336