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In Vivo Imaging of Retinal Hypoxia Using HYPOX-4-Dependent Fluorescence in a Mouse Model of Laser-Induced Retinal Vein Occlusion (RVO)

PURPOSE: To demonstrate the utility of a novel in vivo molecular imaging probe, HYPOX-4, to detect and image retinal hypoxia in real time, in a mouse model of retinal vein occlusion (RVO). METHODS: Retinal vein occlusion was achieved in adult mice by photodynamic retinal vein thrombosis (PRVT). One...

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Detalles Bibliográficos
Autores principales:	Uddin, Md. Imam, Jayagopal, Ashwath, McCollum, Gary W., Yang, Rong, Penn, John S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2017
Materias:	Retina
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531786/ https://www.ncbi.nlm.nih.gov/pubmed/28750413 http://dx.doi.org/10.1167/iovs.16-21187

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