Lunatic fringe-mediated Notch signaling regulates adult hippocampal neural stem cell maintenance

Hippocampal neural stem cells (NSCs) integrate inputs from multiple sources to balance quiescence and activation. Notch signaling plays a key role during this process. Here, we report that Lunatic fringe (Lfng), a key modifier of the Notch receptor, is selectively expressed in NSCs. Further, Lfng in...

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Detalles Bibliográficos
Autores principales: Semerci, Fatih, Choi, William Tin-Shing, Bajic, Aleksandar, Thakkar, Aarohi, Encinas, Juan Manuel, Depreux, Frederic, Segil, Neil, Groves, Andrew K, Maletic-Savatic, Mirjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531831/
https://www.ncbi.nlm.nih.gov/pubmed/28699891
http://dx.doi.org/10.7554/eLife.24660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531831/
https://www.ncbi.nlm.nih.gov/pubmed/28699891
http://dx.doi.org/10.7554/eLife.24660

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