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Lunatic fringe-mediated Notch signaling regulates adult hippocampal neural stem cell maintenance

Hippocampal neural stem cells (NSCs) integrate inputs from multiple sources to balance quiescence and activation. Notch signaling plays a key role during this process. Here, we report that Lunatic fringe (Lfng), a key modifier of the Notch receptor, is selectively expressed in NSCs. Further, Lfng in...

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Detalles Bibliográficos
Autores principales:	Semerci, Fatih, Choi, William Tin-Shing, Bajic, Aleksandar, Thakkar, Aarohi, Encinas, Juan Manuel, Depreux, Frederic, Segil, Neil, Groves, Andrew K, Maletic-Savatic, Mirjana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Developmental Biology and Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531831/ https://www.ncbi.nlm.nih.gov/pubmed/28699891 http://dx.doi.org/10.7554/eLife.24660

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