Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor

Infants with defects in the interleukin 10 receptor (IL10R) develop very early onset inflammatory bowel disease. Whether IL10R regulates lamina propria macrophage function during infant development in mice and whether macrophage-intrinsic IL10R signaling is required to prevent colitis in infancy is...

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Detalles Bibliográficos
Autores principales: Redhu, Naresh S, Bakthavatchalu, Vasudevan, Conaway, Evan A, Shouval, Dror S, Tsou, Amy, Goettel, Jeremy A, Biswas, Amlan, Wang, Chuanwu, Field, Michael, Muller, Werner, Bleich, Andre, Li, Ning, Gerber, Georg K, Bry, Lynn, Fox, James G, Snapper, Scott B, Horwitz, Bruce H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531923/
https://www.ncbi.nlm.nih.gov/pubmed/28678006
http://dx.doi.org/10.7554/eLife.27652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531923/
https://www.ncbi.nlm.nih.gov/pubmed/28678006
http://dx.doi.org/10.7554/eLife.27652

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