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Deletion of Endothelial Cell-Specific Liver Kinase B1 Increases Angiogenesis and Tumor Growth via Vascular Endothelial Growth Factor

Liver kinase B1 (LKB1) is a serine/threonine protein kinase ubiquitously expressed in mammalian cells. It was first identified in Peutz-Jeghers syndrome as a tumor suppressor gene. Whether endothelial LKB1 regulates angiogenesis and tumor growth is unknown. In this study, we generated endothelial ce...

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Detalles Bibliográficos
Autores principales:	Zhang, Wencheng, Ding, Ye, Zhang, Cheng, Lu, Qiulun, Liu, Zhaoyu, Coughlan, Kathleen, Okon, Imoh, Zou, Ming-Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532072/ https://www.ncbi.nlm.nih.gov/pubmed/28346429 http://dx.doi.org/10.1038/onc.2017.61

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