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Microfluidic Cell Retention Device for Perfusion of Mammalian Suspension Culture
Continuous production of biologics, a growing trend in the biopharmaceutical industry, requires a reliable and efficient cell retention device that also maintains cell viability. Current filtration methods, such as tangential flow filtration using hollow-fiber membranes, suffer from membrane fouling...
Autores principales: | Kwon, Taehong, Prentice, Holly, Oliveira, Jonas De, Madziva, Nyasha, Warkiani, Majid Ebrahimi, Hamel, Jean-François P., Han, Jongyoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532224/ https://www.ncbi.nlm.nih.gov/pubmed/28751635 http://dx.doi.org/10.1038/s41598-017-06949-8 |
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