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Hepatocyte specific TIMP3 expression prevents diet dependent fatty liver disease and hepatocellular carcinoma

Non-alcoholic fatty liver disease (NAFLD) encompasses a broad spectrum of conditions, ranging from non-progressive bland steatosis to hepatocarcinoma. Tissue inhibitor of metalloproteinase 3 (Timp3) has a role in the pathogenesis of fatty liver disease associated with obesity and is silenced during...

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Detalles Bibliográficos
Autores principales: Casagrande, Viviana, Mauriello, Alessandro, Bischetti, Simone, Mavilio, Maria, Federici, Massimo, Menghini, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532242/
https://www.ncbi.nlm.nih.gov/pubmed/28751722
http://dx.doi.org/10.1038/s41598-017-06439-x

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