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Hepatocyte specific TIMP3 expression prevents diet dependent fatty liver disease and hepatocellular carcinoma
Non-alcoholic fatty liver disease (NAFLD) encompasses a broad spectrum of conditions, ranging from non-progressive bland steatosis to hepatocarcinoma. Tissue inhibitor of metalloproteinase 3 (Timp3) has a role in the pathogenesis of fatty liver disease associated with obesity and is silenced during...
Autores principales: | Casagrande, Viviana, Mauriello, Alessandro, Bischetti, Simone, Mavilio, Maria, Federici, Massimo, Menghini, Rossella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532242/ https://www.ncbi.nlm.nih.gov/pubmed/28751722 http://dx.doi.org/10.1038/s41598-017-06439-x |
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