Cargando…
Aggregated transthyretin is specifically packaged into placental nano-vesicles in preeclampsia
In preeclampsia, the serum levels of transthyretin, a carrier protein for thyroxine, are elevated. Transthyretin isolated from preeclamptic serum is also aggregated and can induce preeclampsia-like symptoms in pregnant IL10(−/−) mice. Using western blotting, immunofluorescence, ELISA and qRT-PCR, we...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532246/ https://www.ncbi.nlm.nih.gov/pubmed/28751735 http://dx.doi.org/10.1038/s41598-017-07017-x |