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N-glycan mediated adhesion strengthening during pathogen-receptor binding revealed by cell-cell force spectroscopy
Glycan-protein lateral interactions have gained increased attention as important modulators of receptor function, by regulating surface residence time and endocytosis of membrane glycoproteins. The pathogen-recognition receptor DC-SIGN is highly expressed at the membrane of antigen-presenting dendri...
Autores principales: | te Riet, Joost, Joosten, Ben, Reinieren-Beeren, Inge, Figdor, Carl G., Cambi, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532264/ https://www.ncbi.nlm.nih.gov/pubmed/28751750 http://dx.doi.org/10.1038/s41598-017-07220-w |
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