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RhoA phosphorylation mediated by Rho/RhoA-associated kinase pathway improves the anti-freezing potentiality of murine hatched and diapaused blastocysts
Embryonic cryopreservation has a relatively low survival rate because of cytoskeletal damage. However, molecular anti-freezing mechanisms have been largely unexplored. This study investigated the significance of RhoA, involved in embryonic development, and the Rho/RhoA-associated kinase (ROCK) signa...
Autores principales: | Gu, Meichao, Ni, Hemin, Sheng, Xihui, Pauciullo, Alfredo, Liu, Yunhai, Guo, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532275/ https://www.ncbi.nlm.nih.gov/pubmed/28751650 http://dx.doi.org/10.1038/s41598-017-07066-2 |
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