Cargando…

Exploring Animal Models That Resemble Idiopathic Pulmonary Fibrosis

Large multicenter clinical trials have led to two recently approved drugs for patients with idiopathic pulmonary fibrosis (IPF); yet, both of these therapies only slow disease progression and do not provide a definitive cure. Traditionally, preclinical trials have utilized mouse models of bleomycin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tashiro, Jun, Rubio, Gustavo A., Limper, Andrew H., Williams, Kurt, Elliot, Sharon J., Ninou, Ioanna, Aidinis, Vassilis, Tzouvelekis, Argyrios, Glassberg, Marilyn K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532376/ https://www.ncbi.nlm.nih.gov/pubmed/28804709 http://dx.doi.org/10.3389/fmed.2017.00118

Ejemplares similares

Mesenchymal Stem Cells for the Treatment of Idiopathic Pulmonary Fibrosis
por: Tzouvelekis, Argyrios, et al.
Publicado: (2018)

Bleomycin Revisited: A Direct Comparison of the Intratracheal Micro-Spraying and the Oropharyngeal Aspiration Routes of Bleomycin Administration in Mice
por: Barbayianni, Ilianna, et al.
Publicado: (2018)

Autotaxin in Pathophysiology and Pulmonary Fibrosis
por: Ninou, Ioanna, et al.
Publicado: (2018)

What Should Be Chronic: The Animal, the Model, or Both?
por: Rubio, Gustavo A., et al.
Publicado: (2016)

Commonalities Between ARDS, Pulmonary Fibrosis and COVID-19: The Potential of Autotaxin as a Therapeutic Target
por: Ntatsoulis, Konstantinos, et al.
Publicado: (2021)

A role for bronchial epithelial autotaxin in ventilator-induced lung injury
por: Nikitopoulou, Ioanna, et al.
Publicado: (2021)

Orotracheal treprostinil administration attenuates bleomycin-induced lung injury, vascular remodeling, and fibrosis in mice
por: Nikitopoulou, Ioanna, et al.
Publicado: (2019)

Increased lipocalin-2 expression in pulmonary inflammation and fibrosis
por: Galaris, Apostolos, et al.
Publicado: (2023)

Increased Levels of Galectin-3 in Critical COVID-19
por: Nikitopoulou, Ioanna, et al.
Publicado: (2023)

Longitudinal “Real-World” Outcomes of Pirfenidone in Idiopathic Pulmonary Fibrosis in Greece
por: Tzouvelekis, Argyrios, et al.
Publicado: (2017)

Genetic deletion of Autotaxin from CD11b(+) cells decreases the severity of experimental autoimmune encephalomyelitis
por: Ninou, Ioanna, et al.
Publicado: (2020)

Corrigendum: Longitudinal “Real-World” Outcomes of Pirfenidone in Idiopathic Pulmonary Fibrosis in Greece
por: Tzouvelekis, Argyrios, et al.
Publicado: (2018)

Effect of pirfenidone on breathlessness in patients with idiopathic pulmonary fibrosis
por: Glassberg, Marilyn K., et al.
Publicado: (2019)

The Management of Patients With Idiopathic Pulmonary Fibrosis
por: Spagnolo, Paolo, et al.
Publicado: (2018)

Monocyte Count as a Prognostic Biomarker in Patients with Idiopathic Pulmonary Fibrosis
por: Kreuter, Michael, et al.
Publicado: (2021)

SRC and TKS5 mediated podosome formation in fibroblasts promotes extracellular matrix invasion and pulmonary fibrosis
por: Barbayianni, Ilianna, et al.
Publicado: (2023)

Update on therapeutic management of idiopathic pulmonary fibrosis
por: Tzouvelekis, Argyris, et al.
Publicado: (2015)

Effect of pirfenidone in patients with more advanced idiopathic pulmonary fibrosis
por: Costabel, Ulrich, et al.
Publicado: (2019)

Fibromine is a multi-omics database and mining tool for target discovery in pulmonary fibrosis
por: Fanidis, Dionysios, et al.
Publicado: (2021)

Precision medicine advances in idiopathic pulmonary fibrosis
por: Karampitsakos, Theodoros, et al.
Publicado: (2023)

Stem cell therapy for idiopathic pulmonary fibrosis: a protocol proposal
por: Tzouvelekis, Argyris, et al.
Publicado: (2011)

Efficacy and safety of nintedanib in patients with idiopathic pulmonary fibrosis who are elderly or have comorbidities
por: Glaspole, Ian, et al.
Publicado: (2021)

Diagnosis of Idiopathic Pulmonary Fibrosis “Pragmatic Challenges in Clinical Practice”
por: Tzilas, Vasilios, et al.
Publicado: (2017)

Down-regulation of the inhibitor of growth family member 4 (ING4) in different forms of pulmonary fibrosis
por: Tzouvelekis, Argyris, et al.
Publicado: (2009)

Increased Autotaxin Levels in Severe COVID-19, Correlating with IL-6 Levels, Endothelial Dysfunction Biomarkers, and Impaired Functions of Dendritic Cells
por: Nikitopoulou, Ioanna, et al.
Publicado: (2021)

Effect and Safety of Mycophenolate Mofetil in Idiopathic Pulmonary Fibrosis
por: Tzouvelekis, Argyris, et al.
Publicado: (2011)

Metabolic Disorders in Chronic Lung Diseases
por: Papaioannou, Ourania, et al.
Publicado: (2018)

Impact of Depression on Patients With Idiopathic Pulmonary Fibrosis
por: Tzouvelekis, Argyris, et al.
Publicado: (2020)

Expression of PD-1/PD-L1 axis in mediastinal lymph nodes and lung tissue of human and experimental lung fibrosis indicates a potential therapeutic target for idiopathic pulmonary fibrosis
por: Karampitsakos, Theodoros, et al.
Publicado: (2023)

Phase 2 trial to assess lebrikizumab in patients with idiopathic pulmonary fibrosis
por: Maher, Toby M., et al.
Publicado: (2021)

An explainable machine learning-driven proposal of pulmonary fibrosis biomarkers
por: Fanidis, Dionysios, et al.
Publicado: (2023)

The Role of Surgical Lung Biopsy in Antifibrotic Therapy for Idiopathic Pulmonary Fibrosis
por: Limper, Andrew H.
Publicado: (2019)

Cardiovascular Risks, Bleeding Risks, and Clinical Events from 3 Phase III Trials of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis
por: Glassberg, Marilyn K., et al.
Publicado: (2019)

Telomeropathy in Chronic Hypersensitivity Pneumonitis
por: Bouros, Demosthenes, et al.
Publicado: (2019)

Correction to: Cardiovascular Risks, Bleeding Risks, and Clinical Events from 3 Phase III Trials of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis
por: Glassberg, Marilyn K., et al.
Publicado: (2019)

Idiopathic Granulomatous Gastritis Resembling a Gastrointestinal Stromal Tumor
por: Niitsu, Hiroaki, et al.
Publicado: (2012)

Developmental changes in exploration resemble stochastic optimization
por: Giron, Anna P., et al.
Publicado: (2023)

Efficacy and Safety of Pirfenidone in Advanced Versus Non-Advanced Idiopathic Pulmonary Fibrosis: Post-Hoc Analysis of Six Clinical Studies
por: Behr, Jürgen, et al.
Publicado: (2023)

SH2 Domain-Containing Phosphatase-SHP2 Attenuates Fibrotic Responses through Negative Regulation of Mitochondrial Metabolism in Lung Fibroblasts
por: Karampitsakos, Theodoros, et al.
Publicado: (2023)

Efficacy and safety of nintedanib in a Greek multicentre idiopathic pulmonary fibrosis registry: a retrospective, observational, cohort study
por: Antoniou, Katerina, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_s5hs4u6afqki810int14c8v0e7