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Lessons Learned about Neurodegeneration from Microglia and Monocyte Depletion Studies
While bone marrow-derived Ly6C(hi) monocytes can infiltrate the central nervous system (CNS) they are developmentally and functionally distinct from resident microglia. Our understanding of the relative importance of these two populations in the distinct processes of pathogenesis and resolution of i...
Autores principales: | Lund, Harald, Pieber, Melanie, Harris, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532389/ https://www.ncbi.nlm.nih.gov/pubmed/28804456 http://dx.doi.org/10.3389/fnagi.2017.00234 |
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