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Chemotherapy-induced gastrointestinal toxicity is associated with changes in serum and urine metabolome and fecal microbiota in male Sprague–Dawley rats
PURPOSE: Chemotherapy-induced gastrointestinal toxicity (CIGT) is a complex process that involves multiple pathophysiological mechanisms. We have previously shown that commonly used chemotherapeutics 5-fluorouracil, oxaliplatin, and irinotecan damage the intestinal mucosa and increase intestinal per...
Autores principales: | Forsgård, Richard A., Marrachelli, Vannina G., Korpela, Katri, Frias, Rafael, Collado, Maria Carmen, Korpela, Riitta, Monleon, Daniel, Spillmann, Thomas, Österlund, Pia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532424/ https://www.ncbi.nlm.nih.gov/pubmed/28646338 http://dx.doi.org/10.1007/s00280-017-3364-z |
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