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Earlier treatment improves the chances of complete relief from postherpetic neuralgia
BACKGROUND: As herpes zoster progresses via postherpetic neuralgia (PHN) to well-established PHN, it presents its recalcitrant nature to the treatment. At this point, the well-established PHN is fixed as a non-treatable, but manageable chronic painful neuropathic disorder. This study evaluated the i...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Pain Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532529/ https://www.ncbi.nlm.nih.gov/pubmed/28757922 http://dx.doi.org/10.3344/kjp.2017.30.3.214 |
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author | Kang, Dong Hee Kim, Su Young Kim, Hyuck Goo Park, Jung Hyun Kim, Tae Kyun Kim, Kyung Hoon |
author_facet | Kang, Dong Hee Kim, Su Young Kim, Hyuck Goo Park, Jung Hyun Kim, Tae Kyun Kim, Kyung Hoon |
author_sort | Kang, Dong Hee |
collection | PubMed |
description | BACKGROUND: As herpes zoster progresses via postherpetic neuralgia (PHN) to well-established PHN, it presents its recalcitrant nature to the treatment. At this point, the well-established PHN is fixed as a non-treatable, but manageable chronic painful neuropathic disorder. This study evaluated the incidence of complete relief from PHN according to PHN duration at their first visit, and the other factors influencing it. METHODS: A retrospective chart review was performed on patients with PHN at a university-based pain clinic over 7 years. The responders were defined as patients who had complete relief from pain after 1 year of active treatment. Age, sex, PHN duration at their first visit, dermatomal distribution, and underlying disorders were compared in the responder and non-responder groups. Responders were also compared according to these factors. RESULTS: Among 117 PHN patients (M/F = 48/69), 35 patients (29.9%) had complete relief from PHN. Mean ages were 64.3 ± 10.6 and 66.9 ± 10.7 years, numbers of male to female patients were 11/24 and 37/45, and mean durations of PHN at their first visit were 8.5 ± 6.3 and 15.3 ± 10.7 months in the responder and non- responder groups, respectively. In addition, PHN patients who visited the clinic before 9 months showed a better result. Dermatomal distribution and underlying disorders did not show significant differences. CONCLUSIONS: Almost 30% of PHN patients received complete relief. Those who sought treatment in a pain clinic before 9 months received a better result. |
format | Online Article Text |
id | pubmed-5532529 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | The Korean Pain Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-55325292017-07-28 Earlier treatment improves the chances of complete relief from postherpetic neuralgia Kang, Dong Hee Kim, Su Young Kim, Hyuck Goo Park, Jung Hyun Kim, Tae Kyun Kim, Kyung Hoon Korean J Pain Original Article BACKGROUND: As herpes zoster progresses via postherpetic neuralgia (PHN) to well-established PHN, it presents its recalcitrant nature to the treatment. At this point, the well-established PHN is fixed as a non-treatable, but manageable chronic painful neuropathic disorder. This study evaluated the incidence of complete relief from PHN according to PHN duration at their first visit, and the other factors influencing it. METHODS: A retrospective chart review was performed on patients with PHN at a university-based pain clinic over 7 years. The responders were defined as patients who had complete relief from pain after 1 year of active treatment. Age, sex, PHN duration at their first visit, dermatomal distribution, and underlying disorders were compared in the responder and non-responder groups. Responders were also compared according to these factors. RESULTS: Among 117 PHN patients (M/F = 48/69), 35 patients (29.9%) had complete relief from PHN. Mean ages were 64.3 ± 10.6 and 66.9 ± 10.7 years, numbers of male to female patients were 11/24 and 37/45, and mean durations of PHN at their first visit were 8.5 ± 6.3 and 15.3 ± 10.7 months in the responder and non- responder groups, respectively. In addition, PHN patients who visited the clinic before 9 months showed a better result. Dermatomal distribution and underlying disorders did not show significant differences. CONCLUSIONS: Almost 30% of PHN patients received complete relief. Those who sought treatment in a pain clinic before 9 months received a better result. The Korean Pain Society 2017-07 2017-06-30 /pmc/articles/PMC5532529/ /pubmed/28757922 http://dx.doi.org/10.3344/kjp.2017.30.3.214 Text en Copyright © The Korean Pain Society, 2017 http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kang, Dong Hee Kim, Su Young Kim, Hyuck Goo Park, Jung Hyun Kim, Tae Kyun Kim, Kyung Hoon Earlier treatment improves the chances of complete relief from postherpetic neuralgia |
title | Earlier treatment improves the chances of complete relief from postherpetic neuralgia |
title_full | Earlier treatment improves the chances of complete relief from postherpetic neuralgia |
title_fullStr | Earlier treatment improves the chances of complete relief from postherpetic neuralgia |
title_full_unstemmed | Earlier treatment improves the chances of complete relief from postherpetic neuralgia |
title_short | Earlier treatment improves the chances of complete relief from postherpetic neuralgia |
title_sort | earlier treatment improves the chances of complete relief from postherpetic neuralgia |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532529/ https://www.ncbi.nlm.nih.gov/pubmed/28757922 http://dx.doi.org/10.3344/kjp.2017.30.3.214 |
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