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Earlier treatment improves the chances of complete relief from postherpetic neuralgia

BACKGROUND: As herpes zoster progresses via postherpetic neuralgia (PHN) to well-established PHN, it presents its recalcitrant nature to the treatment. At this point, the well-established PHN is fixed as a non-treatable, but manageable chronic painful neuropathic disorder. This study evaluated the i...

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Autores principales: Kang, Dong Hee, Kim, Su Young, Kim, Hyuck Goo, Park, Jung Hyun, Kim, Tae Kyun, Kim, Kyung Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532529/
https://www.ncbi.nlm.nih.gov/pubmed/28757922
http://dx.doi.org/10.3344/kjp.2017.30.3.214
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author Kang, Dong Hee
Kim, Su Young
Kim, Hyuck Goo
Park, Jung Hyun
Kim, Tae Kyun
Kim, Kyung Hoon
author_facet Kang, Dong Hee
Kim, Su Young
Kim, Hyuck Goo
Park, Jung Hyun
Kim, Tae Kyun
Kim, Kyung Hoon
author_sort Kang, Dong Hee
collection PubMed
description BACKGROUND: As herpes zoster progresses via postherpetic neuralgia (PHN) to well-established PHN, it presents its recalcitrant nature to the treatment. At this point, the well-established PHN is fixed as a non-treatable, but manageable chronic painful neuropathic disorder. This study evaluated the incidence of complete relief from PHN according to PHN duration at their first visit, and the other factors influencing it. METHODS: A retrospective chart review was performed on patients with PHN at a university-based pain clinic over 7 years. The responders were defined as patients who had complete relief from pain after 1 year of active treatment. Age, sex, PHN duration at their first visit, dermatomal distribution, and underlying disorders were compared in the responder and non-responder groups. Responders were also compared according to these factors. RESULTS: Among 117 PHN patients (M/F = 48/69), 35 patients (29.9%) had complete relief from PHN. Mean ages were 64.3 ± 10.6 and 66.9 ± 10.7 years, numbers of male to female patients were 11/24 and 37/45, and mean durations of PHN at their first visit were 8.5 ± 6.3 and 15.3 ± 10.7 months in the responder and non- responder groups, respectively. In addition, PHN patients who visited the clinic before 9 months showed a better result. Dermatomal distribution and underlying disorders did not show significant differences. CONCLUSIONS: Almost 30% of PHN patients received complete relief. Those who sought treatment in a pain clinic before 9 months received a better result.
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spelling pubmed-55325292017-07-28 Earlier treatment improves the chances of complete relief from postherpetic neuralgia Kang, Dong Hee Kim, Su Young Kim, Hyuck Goo Park, Jung Hyun Kim, Tae Kyun Kim, Kyung Hoon Korean J Pain Original Article BACKGROUND: As herpes zoster progresses via postherpetic neuralgia (PHN) to well-established PHN, it presents its recalcitrant nature to the treatment. At this point, the well-established PHN is fixed as a non-treatable, but manageable chronic painful neuropathic disorder. This study evaluated the incidence of complete relief from PHN according to PHN duration at their first visit, and the other factors influencing it. METHODS: A retrospective chart review was performed on patients with PHN at a university-based pain clinic over 7 years. The responders were defined as patients who had complete relief from pain after 1 year of active treatment. Age, sex, PHN duration at their first visit, dermatomal distribution, and underlying disorders were compared in the responder and non-responder groups. Responders were also compared according to these factors. RESULTS: Among 117 PHN patients (M/F = 48/69), 35 patients (29.9%) had complete relief from PHN. Mean ages were 64.3 ± 10.6 and 66.9 ± 10.7 years, numbers of male to female patients were 11/24 and 37/45, and mean durations of PHN at their first visit were 8.5 ± 6.3 and 15.3 ± 10.7 months in the responder and non- responder groups, respectively. In addition, PHN patients who visited the clinic before 9 months showed a better result. Dermatomal distribution and underlying disorders did not show significant differences. CONCLUSIONS: Almost 30% of PHN patients received complete relief. Those who sought treatment in a pain clinic before 9 months received a better result. The Korean Pain Society 2017-07 2017-06-30 /pmc/articles/PMC5532529/ /pubmed/28757922 http://dx.doi.org/10.3344/kjp.2017.30.3.214 Text en Copyright © The Korean Pain Society, 2017 http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kang, Dong Hee
Kim, Su Young
Kim, Hyuck Goo
Park, Jung Hyun
Kim, Tae Kyun
Kim, Kyung Hoon
Earlier treatment improves the chances of complete relief from postherpetic neuralgia
title Earlier treatment improves the chances of complete relief from postherpetic neuralgia
title_full Earlier treatment improves the chances of complete relief from postherpetic neuralgia
title_fullStr Earlier treatment improves the chances of complete relief from postherpetic neuralgia
title_full_unstemmed Earlier treatment improves the chances of complete relief from postherpetic neuralgia
title_short Earlier treatment improves the chances of complete relief from postherpetic neuralgia
title_sort earlier treatment improves the chances of complete relief from postherpetic neuralgia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532529/
https://www.ncbi.nlm.nih.gov/pubmed/28757922
http://dx.doi.org/10.3344/kjp.2017.30.3.214
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