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Phenotypic Plasticity and Cell Fate Decisions in Cancer: Insights from Dynamical Systems Theory

Waddington’s epigenetic landscape, a famous metaphor in developmental biology, depicts how a stem cell progresses from an undifferentiated phenotype to a differentiated one. The concept of “landscape” in the context of dynamical systems theory represents a high-dimensional space, in which each cell...

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Detalles Bibliográficos
Autores principales:	Jia, Dongya, Jolly, Mohit Kumar, Kulkarni, Prakash, Levine, Herbert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532606/ https://www.ncbi.nlm.nih.gov/pubmed/28640191 http://dx.doi.org/10.3390/cancers9070070

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