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Role and Therapeutic Targeting of the HGF/MET Pathway in Glioblastoma

Glioblastoma (GBM) is a lethal brain tumor with dismal prognosis. Current therapeutic options, consisting of surgery, chemotherapy and radiation, have only served to marginally increase patient survival. Receptor tyrosine kinases (RTKs) are dysregulated in approximately 90% of GBM; attributed to thi...

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Detalles Bibliográficos
Autores principales:	Cruickshanks, Nichola, Zhang, Ying, Yuan, Fang, Pahuski, Mary, Gibert, Myron, Abounader, Roger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532623/ https://www.ncbi.nlm.nih.gov/pubmed/28696366 http://dx.doi.org/10.3390/cancers9070087

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