Isoprenoids from the Soft Coral Sarcophyton glaucum

Five new isoprenoids, 3,4,8,16-tetra-epi-lobocrasol (1), 1,15β-epoxy-deoxysarcophine (2), 3,4-dihydro-4α,7β,8α-trihydroxy-Δ(2)-sarcophine (3), ent-sarcophyolide E (4), and 16-deacetyl- halicrasterol B (5) and ten known compounds 6‒15, were characterized from the marine soft coral Sarcophyton glaucum...

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Autores principales: Chao, Chih-Hua, Li, Wen-Liang, Huang, Chiung-Yao, Ahmed, Atallah F., Dai, Chang-Feng, Wu, Yang-Chang, Lu, Mei-Chin, Liaw, Chih-Chuang, Sheu, Jyh-Horng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532644/
https://www.ncbi.nlm.nih.gov/pubmed/28653983
http://dx.doi.org/10.3390/md15070202
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author Chao, Chih-Hua
Li, Wen-Liang
Huang, Chiung-Yao
Ahmed, Atallah F.
Dai, Chang-Feng
Wu, Yang-Chang
Lu, Mei-Chin
Liaw, Chih-Chuang
Sheu, Jyh-Horng
author_facet Chao, Chih-Hua
Li, Wen-Liang
Huang, Chiung-Yao
Ahmed, Atallah F.
Dai, Chang-Feng
Wu, Yang-Chang
Lu, Mei-Chin
Liaw, Chih-Chuang
Sheu, Jyh-Horng
author_sort Chao, Chih-Hua
collection PubMed
description Five new isoprenoids, 3,4,8,16-tetra-epi-lobocrasol (1), 1,15β-epoxy-deoxysarcophine (2), 3,4-dihydro-4α,7β,8α-trihydroxy-Δ(2)-sarcophine (3), ent-sarcophyolide E (4), and 16-deacetyl- halicrasterol B (5) and ten known compounds 6‒15, were characterized from the marine soft coral Sarcophyton glaucum, collected off Taitung coastline. Their structures were defined by analyzing spectra data, especially 2D NMR and electronic circular dichroism (ECD). The structure of the known compound lobocrasol (7) was revised. Cytotoxicity potential of the isolated compounds was reported, too.
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spelling pubmed-55326442017-08-09 Isoprenoids from the Soft Coral Sarcophyton glaucum Chao, Chih-Hua Li, Wen-Liang Huang, Chiung-Yao Ahmed, Atallah F. Dai, Chang-Feng Wu, Yang-Chang Lu, Mei-Chin Liaw, Chih-Chuang Sheu, Jyh-Horng Mar Drugs Article Five new isoprenoids, 3,4,8,16-tetra-epi-lobocrasol (1), 1,15β-epoxy-deoxysarcophine (2), 3,4-dihydro-4α,7β,8α-trihydroxy-Δ(2)-sarcophine (3), ent-sarcophyolide E (4), and 16-deacetyl- halicrasterol B (5) and ten known compounds 6‒15, were characterized from the marine soft coral Sarcophyton glaucum, collected off Taitung coastline. Their structures were defined by analyzing spectra data, especially 2D NMR and electronic circular dichroism (ECD). The structure of the known compound lobocrasol (7) was revised. Cytotoxicity potential of the isolated compounds was reported, too. MDPI 2017-06-27 /pmc/articles/PMC5532644/ /pubmed/28653983 http://dx.doi.org/10.3390/md15070202 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chao, Chih-Hua
Li, Wen-Liang
Huang, Chiung-Yao
Ahmed, Atallah F.
Dai, Chang-Feng
Wu, Yang-Chang
Lu, Mei-Chin
Liaw, Chih-Chuang
Sheu, Jyh-Horng
Isoprenoids from the Soft Coral Sarcophyton glaucum
title Isoprenoids from the Soft Coral Sarcophyton glaucum
title_full Isoprenoids from the Soft Coral Sarcophyton glaucum
title_fullStr Isoprenoids from the Soft Coral Sarcophyton glaucum
title_full_unstemmed Isoprenoids from the Soft Coral Sarcophyton glaucum
title_short Isoprenoids from the Soft Coral Sarcophyton glaucum
title_sort isoprenoids from the soft coral sarcophyton glaucum
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532644/
https://www.ncbi.nlm.nih.gov/pubmed/28653983
http://dx.doi.org/10.3390/md15070202
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