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Mertensene, a Halogenated Monoterpene, Induces G2/M Cell Cycle Arrest and Caspase Dependent Apoptosis of Human Colon Adenocarcinoma HT29 Cell Line through the Modulation of ERK-1/-2, AKT and NF-κB Signaling

Conventional treatment of advanced colorectal cancer is associated with tumor resistance and toxicity towards normal tissues. Therefore, development of effective anticancer therapeutic alternatives is still urgently required. Nowadays, marine secondary metabolites have been extensively investigated...

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Detalles Bibliográficos
Autores principales: Tarhouni-Jabberi, Safa, Zakraoui, Ons, Ioannou, Efstathia, Riahi-Chebbi, Ichrak, Haoues, Meriam, Roussis, Vassilios, Kharrat, Riadh, Essafi-Benkhadir, Khadija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532663/
https://www.ncbi.nlm.nih.gov/pubmed/28726723
http://dx.doi.org/10.3390/md15070221