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Mertensene, a Halogenated Monoterpene, Induces G2/M Cell Cycle Arrest and Caspase Dependent Apoptosis of Human Colon Adenocarcinoma HT29 Cell Line through the Modulation of ERK-1/-2, AKT and NF-κB Signaling
Conventional treatment of advanced colorectal cancer is associated with tumor resistance and toxicity towards normal tissues. Therefore, development of effective anticancer therapeutic alternatives is still urgently required. Nowadays, marine secondary metabolites have been extensively investigated...
Autores principales: | Tarhouni-Jabberi, Safa, Zakraoui, Ons, Ioannou, Efstathia, Riahi-Chebbi, Ichrak, Haoues, Meriam, Roussis, Vassilios, Kharrat, Riadh, Essafi-Benkhadir, Khadija |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532663/ https://www.ncbi.nlm.nih.gov/pubmed/28726723 http://dx.doi.org/10.3390/md15070221 |
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