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Mechanistic Investigation of the Specific Anticancer Property of Artemisinin and Its Combination with Aminolevulinic Acid for Enhanced Anticolorectal Cancer Activity
[Image: see text] The antimalarial artemisinin (ART) possesses anticancer activity, but its underlying mechanism remains largely unclear. Using a chemical proteomics approach with artemisinin-based activity probes, we identified over 300 specific ART targets. This reveals an anticancer mechanism whe...
Autores principales: | Wang, Jigang, Zhang, Jianbin, Shi, Yin, Xu, Chengchao, Zhang, Chongjing, Wong, Yin Kwan, Lee, Yew Mun, Krishna, Sanjeev, He, Yingke, Lim, Teck Kwang, Sim, Weiying, Hua, Zi-Chun, Shen, Han-Ming, Lin, Qingsong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532725/ https://www.ncbi.nlm.nih.gov/pubmed/28776016 http://dx.doi.org/10.1021/acscentsci.7b00156 |
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