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Outcome and management of spinal tuberculosis according to severity at a tertiary referral center

OBJECTIVE: Anti-tuberculosis (TB) treatment remains the mainstay of treatment of spinal TB. There is a lack of consensus regarding the timing of interventional procedures and surgery in the patients with spinal TB. This study aims to prospectively study the clinical outcome and management in patient...

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Autores principales: Bodapati, Prasad Chandramouliswara, Vemula, Ramesh Chandra Venkata, Mohammad, Ameen Abdul, Mohan, Alladi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532929/
https://www.ncbi.nlm.nih.gov/pubmed/28761522
http://dx.doi.org/10.4103/1793-5482.180924
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author Bodapati, Prasad Chandramouliswara
Vemula, Ramesh Chandra Venkata
Mohammad, Ameen Abdul
Mohan, Alladi
author_facet Bodapati, Prasad Chandramouliswara
Vemula, Ramesh Chandra Venkata
Mohammad, Ameen Abdul
Mohan, Alladi
author_sort Bodapati, Prasad Chandramouliswara
collection PubMed
description OBJECTIVE: Anti-tuberculosis (TB) treatment remains the mainstay of treatment of spinal TB. There is a lack of consensus regarding the timing of interventional procedures and surgery in the patients with spinal TB. This study aims to prospectively study the clinical outcome and management in patients presenting with spinal TB at our tertiary referral center and teaching hospital. METHODS: Data were collected prospectively from 48 patients treated for spinal TB presenting to us from August 2011 to December 2012. All the patients were followed-up for the duration of anti-TB treatment. RESULTS: The categorization of patients into different management groups was based on the clinical and radiological findings at the time of diagnosis. The patients with mild disease (n = 23) were successfully managed with anti-TB treatment alone. The other 25 patients needed an intervention either in the form of pigtail catheter drainage of the paravertebral collection (n = 18) or an extensive surgical debridement followed by the fusion techniques (n = 7). All the patients responded well to the treatment, and there were no significant complications in any of the patients. It had been observed that various stages of spinal TB demand different approaches for the treatment in the form of either chemotherapy alone, chemotherapy with pigtail drainage of the paravertebral collection, or surgery in conjunction with chemotherapy. CONCLUSIONS: Judicious use of pigtail drainage and surgical intervention in addition to anti TB treatment can be rewarding in the patients with spinal TB.
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spelling pubmed-55329292017-07-31 Outcome and management of spinal tuberculosis according to severity at a tertiary referral center Bodapati, Prasad Chandramouliswara Vemula, Ramesh Chandra Venkata Mohammad, Ameen Abdul Mohan, Alladi Asian J Neurosurg Original Article OBJECTIVE: Anti-tuberculosis (TB) treatment remains the mainstay of treatment of spinal TB. There is a lack of consensus regarding the timing of interventional procedures and surgery in the patients with spinal TB. This study aims to prospectively study the clinical outcome and management in patients presenting with spinal TB at our tertiary referral center and teaching hospital. METHODS: Data were collected prospectively from 48 patients treated for spinal TB presenting to us from August 2011 to December 2012. All the patients were followed-up for the duration of anti-TB treatment. RESULTS: The categorization of patients into different management groups was based on the clinical and radiological findings at the time of diagnosis. The patients with mild disease (n = 23) were successfully managed with anti-TB treatment alone. The other 25 patients needed an intervention either in the form of pigtail catheter drainage of the paravertebral collection (n = 18) or an extensive surgical debridement followed by the fusion techniques (n = 7). All the patients responded well to the treatment, and there were no significant complications in any of the patients. It had been observed that various stages of spinal TB demand different approaches for the treatment in the form of either chemotherapy alone, chemotherapy with pigtail drainage of the paravertebral collection, or surgery in conjunction with chemotherapy. CONCLUSIONS: Judicious use of pigtail drainage and surgical intervention in addition to anti TB treatment can be rewarding in the patients with spinal TB. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5532929/ /pubmed/28761522 http://dx.doi.org/10.4103/1793-5482.180924 Text en Copyright: © 2016 Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Bodapati, Prasad Chandramouliswara
Vemula, Ramesh Chandra Venkata
Mohammad, Ameen Abdul
Mohan, Alladi
Outcome and management of spinal tuberculosis according to severity at a tertiary referral center
title Outcome and management of spinal tuberculosis according to severity at a tertiary referral center
title_full Outcome and management of spinal tuberculosis according to severity at a tertiary referral center
title_fullStr Outcome and management of spinal tuberculosis according to severity at a tertiary referral center
title_full_unstemmed Outcome and management of spinal tuberculosis according to severity at a tertiary referral center
title_short Outcome and management of spinal tuberculosis according to severity at a tertiary referral center
title_sort outcome and management of spinal tuberculosis according to severity at a tertiary referral center
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532929/
https://www.ncbi.nlm.nih.gov/pubmed/28761522
http://dx.doi.org/10.4103/1793-5482.180924
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