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Tollip Deficiency Alters Atherosclerosis and Steatosis by Disrupting Lipophagy

BACKGROUND: Compromised lipophagy with unknown mechanisms may be critically involved in the intracellular accumulation of lipids, contributing to elevated atherosclerosis and liver steatosis. We hypothesize that toll‐interacting protein (Tollip), a key innate immune molecule involved in the fusion o...

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Detalles Bibliográficos
Autores principales: Chen, Keqiang, Yuan, Ruoxi, Zhang, Yao, Geng, Shuo, Li, Liwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532987/
https://www.ncbi.nlm.nih.gov/pubmed/28396568
http://dx.doi.org/10.1161/JAHA.116.004078

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