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Monocrotaline Induces Endothelial Injury and Pulmonary Hypertension by Targeting the Extracellular Calcium–Sensing Receptor

BACKGROUND: Monocrotaline has been widely used to establish an animal model of pulmonary hypertension. The molecular target underlying monocrotaline‐induced pulmonary artery endothelial injury and pulmonary hypertension remains unknown. The extracellular calcium–sensing receptor (CaSR) and particula...

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Detalles Bibliográficos
Autores principales: Xiao, Rui, Su, Yuan, Feng, Tian, Sun, Mengxiang, Liu, Bingxun, Zhang, Jiwei, Lu, Yankai, Li, Jiansha, Wang, Tao, Zhu, Liping, Hu, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533002/
https://www.ncbi.nlm.nih.gov/pubmed/28330842
http://dx.doi.org/10.1161/JAHA.116.004865

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