MSDB: A Comprehensive Database of Simple Sequence Repeats

Microsatellites, also known as Simple Sequence Repeats (SSRs), are short tandem repeats of 1–6 nt motifs present in all genomes, particularly eukaryotes. Besides their usefulness as genome markers, SSRs have been shown to perform important regulatory functions, and variations in their length at codi...

Descripción completa

Detalles Bibliográficos
Autores principales: Avvaru, Akshay Kumar, Saxena, Saketh, Sowpati, Divya Tej, Mishra, Rakesh Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533116/
https://www.ncbi.nlm.nih.gov/pubmed/28854643
http://dx.doi.org/10.1093/gbe/evx132
Descripción
Sumario:Microsatellites, also known as Simple Sequence Repeats (SSRs), are short tandem repeats of 1–6 nt motifs present in all genomes, particularly eukaryotes. Besides their usefulness as genome markers, SSRs have been shown to perform important regulatory functions, and variations in their length at coding regions are linked to several disorders in humans. Microsatellites show a taxon-specific enrichment in eukaryotic genomes, and some may be functional. MSDB (Microsatellite Database) is a collection of >650 million SSRs from 6,893 species including Bacteria, Archaea, Fungi, Plants, and Animals. This database is by far the most exhaustive resource to access and analyze SSR data of multiple species. In addition to exploring data in a customizable tabular format, users can view and compare the data of multiple species simultaneously using our interactive plotting system. MSDB is developed using the Django framework and MySQL. It is freely available at http://tdb.ccmb.res.in/msdb.

Ejemplares similares