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MSDB: A Comprehensive Database of Simple Sequence Repeats

Microsatellites, also known as Simple Sequence Repeats (SSRs), are short tandem repeats of 1–6 nt motifs present in all genomes, particularly eukaryotes. Besides their usefulness as genome markers, SSRs have been shown to perform important regulatory functions, and variations in their length at codi...

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Autores principales: Avvaru, Akshay Kumar, Saxena, Saketh, Sowpati, Divya Tej, Mishra, Rakesh Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533116/
https://www.ncbi.nlm.nih.gov/pubmed/28854643
http://dx.doi.org/10.1093/gbe/evx132
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author Avvaru, Akshay Kumar
Saxena, Saketh
Sowpati, Divya Tej
Mishra, Rakesh Kumar
author_facet Avvaru, Akshay Kumar
Saxena, Saketh
Sowpati, Divya Tej
Mishra, Rakesh Kumar
author_sort Avvaru, Akshay Kumar
collection PubMed
description Microsatellites, also known as Simple Sequence Repeats (SSRs), are short tandem repeats of 1–6 nt motifs present in all genomes, particularly eukaryotes. Besides their usefulness as genome markers, SSRs have been shown to perform important regulatory functions, and variations in their length at coding regions are linked to several disorders in humans. Microsatellites show a taxon-specific enrichment in eukaryotic genomes, and some may be functional. MSDB (Microsatellite Database) is a collection of >650 million SSRs from 6,893 species including Bacteria, Archaea, Fungi, Plants, and Animals. This database is by far the most exhaustive resource to access and analyze SSR data of multiple species. In addition to exploring data in a customizable tabular format, users can view and compare the data of multiple species simultaneously using our interactive plotting system. MSDB is developed using the Django framework and MySQL. It is freely available at http://tdb.ccmb.res.in/msdb.
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spelling pubmed-55331162017-07-31 MSDB: A Comprehensive Database of Simple Sequence Repeats Avvaru, Akshay Kumar Saxena, Saketh Sowpati, Divya Tej Mishra, Rakesh Kumar Genome Biol Evol Genome Resources Microsatellites, also known as Simple Sequence Repeats (SSRs), are short tandem repeats of 1–6 nt motifs present in all genomes, particularly eukaryotes. Besides their usefulness as genome markers, SSRs have been shown to perform important regulatory functions, and variations in their length at coding regions are linked to several disorders in humans. Microsatellites show a taxon-specific enrichment in eukaryotic genomes, and some may be functional. MSDB (Microsatellite Database) is a collection of >650 million SSRs from 6,893 species including Bacteria, Archaea, Fungi, Plants, and Animals. This database is by far the most exhaustive resource to access and analyze SSR data of multiple species. In addition to exploring data in a customizable tabular format, users can view and compare the data of multiple species simultaneously using our interactive plotting system. MSDB is developed using the Django framework and MySQL. It is freely available at http://tdb.ccmb.res.in/msdb. Oxford University Press 2017-07-14 /pmc/articles/PMC5533116/ /pubmed/28854643 http://dx.doi.org/10.1093/gbe/evx132 Text en © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Genome Resources
Avvaru, Akshay Kumar
Saxena, Saketh
Sowpati, Divya Tej
Mishra, Rakesh Kumar
MSDB: A Comprehensive Database of Simple Sequence Repeats
title MSDB: A Comprehensive Database of Simple Sequence Repeats
title_full MSDB: A Comprehensive Database of Simple Sequence Repeats
title_fullStr MSDB: A Comprehensive Database of Simple Sequence Repeats
title_full_unstemmed MSDB: A Comprehensive Database of Simple Sequence Repeats
title_short MSDB: A Comprehensive Database of Simple Sequence Repeats
title_sort msdb: a comprehensive database of simple sequence repeats
topic Genome Resources
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533116/
https://www.ncbi.nlm.nih.gov/pubmed/28854643
http://dx.doi.org/10.1093/gbe/evx132
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