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MSDB: A Comprehensive Database of Simple Sequence Repeats
Microsatellites, also known as Simple Sequence Repeats (SSRs), are short tandem repeats of 1–6 nt motifs present in all genomes, particularly eukaryotes. Besides their usefulness as genome markers, SSRs have been shown to perform important regulatory functions, and variations in their length at codi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533116/ https://www.ncbi.nlm.nih.gov/pubmed/28854643 http://dx.doi.org/10.1093/gbe/evx132 |
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author | Avvaru, Akshay Kumar Saxena, Saketh Sowpati, Divya Tej Mishra, Rakesh Kumar |
author_facet | Avvaru, Akshay Kumar Saxena, Saketh Sowpati, Divya Tej Mishra, Rakesh Kumar |
author_sort | Avvaru, Akshay Kumar |
collection | PubMed |
description | Microsatellites, also known as Simple Sequence Repeats (SSRs), are short tandem repeats of 1–6 nt motifs present in all genomes, particularly eukaryotes. Besides their usefulness as genome markers, SSRs have been shown to perform important regulatory functions, and variations in their length at coding regions are linked to several disorders in humans. Microsatellites show a taxon-specific enrichment in eukaryotic genomes, and some may be functional. MSDB (Microsatellite Database) is a collection of >650 million SSRs from 6,893 species including Bacteria, Archaea, Fungi, Plants, and Animals. This database is by far the most exhaustive resource to access and analyze SSR data of multiple species. In addition to exploring data in a customizable tabular format, users can view and compare the data of multiple species simultaneously using our interactive plotting system. MSDB is developed using the Django framework and MySQL. It is freely available at http://tdb.ccmb.res.in/msdb. |
format | Online Article Text |
id | pubmed-5533116 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-55331162017-07-31 MSDB: A Comprehensive Database of Simple Sequence Repeats Avvaru, Akshay Kumar Saxena, Saketh Sowpati, Divya Tej Mishra, Rakesh Kumar Genome Biol Evol Genome Resources Microsatellites, also known as Simple Sequence Repeats (SSRs), are short tandem repeats of 1–6 nt motifs present in all genomes, particularly eukaryotes. Besides their usefulness as genome markers, SSRs have been shown to perform important regulatory functions, and variations in their length at coding regions are linked to several disorders in humans. Microsatellites show a taxon-specific enrichment in eukaryotic genomes, and some may be functional. MSDB (Microsatellite Database) is a collection of >650 million SSRs from 6,893 species including Bacteria, Archaea, Fungi, Plants, and Animals. This database is by far the most exhaustive resource to access and analyze SSR data of multiple species. In addition to exploring data in a customizable tabular format, users can view and compare the data of multiple species simultaneously using our interactive plotting system. MSDB is developed using the Django framework and MySQL. It is freely available at http://tdb.ccmb.res.in/msdb. Oxford University Press 2017-07-14 /pmc/articles/PMC5533116/ /pubmed/28854643 http://dx.doi.org/10.1093/gbe/evx132 Text en © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Genome Resources Avvaru, Akshay Kumar Saxena, Saketh Sowpati, Divya Tej Mishra, Rakesh Kumar MSDB: A Comprehensive Database of Simple Sequence Repeats |
title | MSDB: A Comprehensive Database of Simple Sequence Repeats |
title_full | MSDB: A Comprehensive Database of Simple Sequence Repeats |
title_fullStr | MSDB: A Comprehensive Database of Simple Sequence Repeats |
title_full_unstemmed | MSDB: A Comprehensive Database of Simple Sequence Repeats |
title_short | MSDB: A Comprehensive Database of Simple Sequence Repeats |
title_sort | msdb: a comprehensive database of simple sequence repeats |
topic | Genome Resources |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533116/ https://www.ncbi.nlm.nih.gov/pubmed/28854643 http://dx.doi.org/10.1093/gbe/evx132 |
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