Cargando…
Change in Use of Sleep Medications After Gastric Bypass Surgery or Intensive Lifestyle Treatment in Adults with Obesity
OBJECTIVE: To examine the change in use of hypnotics and/or sedatives after gastric bypass surgery or intensive lifestyle modification in adults with obesity. METHODS: Adults with obesity who underwent gastric bypass surgery or initiated intensive lifestyle modification between 2007 and 2012 were id...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533175/ https://www.ncbi.nlm.nih.gov/pubmed/28660652 http://dx.doi.org/10.1002/oby.21908 |
_version_ | 1783253588690075648 |
---|---|
author | Ng, Winda L. Peeters, Anna Näslund, Ingmar Ottosson, Johan Johansson, Kari Marcus, Claude Shaw, Jonathan E. Bruze, Gustaf Sundström, Johan Neovius, Martin |
author_facet | Ng, Winda L. Peeters, Anna Näslund, Ingmar Ottosson, Johan Johansson, Kari Marcus, Claude Shaw, Jonathan E. Bruze, Gustaf Sundström, Johan Neovius, Martin |
author_sort | Ng, Winda L. |
collection | PubMed |
description | OBJECTIVE: To examine the change in use of hypnotics and/or sedatives after gastric bypass surgery or intensive lifestyle modification in adults with obesity. METHODS: Adults with obesity who underwent gastric bypass surgery or initiated intensive lifestyle modification between 2007 and 2012 were identified through the Scandinavian Obesity Surgery Registry and a Swedish commercial weight loss database. The two cohorts were matched on BMI, age, sex, education, history of hypnotics and/or sedatives use, and treatment year (surgery n = 20,626; lifestyle n = 11,973; 77% women, mean age 41 years, mean BMI 41 kg/m(2)). The proportion of participants with filled hypnotics and/or sedatives prescriptions was compared yearly for 3 years. RESULTS: In the matched treatment cohorts, 4% had filled prescriptions for hypnotics and/or sedatives during the year before treatment. At 1 year follow‐up, following an average weight loss of 37 kg and 18 kg in the surgery and intensive lifestyle cohorts, respectively, this proportion had increased to 7% in the surgery cohort but remained at 4% in the intensive lifestyle cohort (risk ratio 1.7; 95% CI: 1.4‐2.1); at 2 years, the proportion had increased to 11% versus 5% (risk ratio 2.0; 95% CI: 1.7‐2.4); and at 3 years, it had increased to 14% versus 6% (risk ratio 2.2; 95% CI: 1.9‐2.6). CONCLUSIONS: Gastric bypass surgery was associated with increased use of hypnotics and/or sedatives compared with intensive lifestyle modification. |
format | Online Article Text |
id | pubmed-5533175 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-55331752017-09-18 Change in Use of Sleep Medications After Gastric Bypass Surgery or Intensive Lifestyle Treatment in Adults with Obesity Ng, Winda L. Peeters, Anna Näslund, Ingmar Ottosson, Johan Johansson, Kari Marcus, Claude Shaw, Jonathan E. Bruze, Gustaf Sundström, Johan Neovius, Martin Obesity (Silver Spring) Original Articles OBJECTIVE: To examine the change in use of hypnotics and/or sedatives after gastric bypass surgery or intensive lifestyle modification in adults with obesity. METHODS: Adults with obesity who underwent gastric bypass surgery or initiated intensive lifestyle modification between 2007 and 2012 were identified through the Scandinavian Obesity Surgery Registry and a Swedish commercial weight loss database. The two cohorts were matched on BMI, age, sex, education, history of hypnotics and/or sedatives use, and treatment year (surgery n = 20,626; lifestyle n = 11,973; 77% women, mean age 41 years, mean BMI 41 kg/m(2)). The proportion of participants with filled hypnotics and/or sedatives prescriptions was compared yearly for 3 years. RESULTS: In the matched treatment cohorts, 4% had filled prescriptions for hypnotics and/or sedatives during the year before treatment. At 1 year follow‐up, following an average weight loss of 37 kg and 18 kg in the surgery and intensive lifestyle cohorts, respectively, this proportion had increased to 7% in the surgery cohort but remained at 4% in the intensive lifestyle cohort (risk ratio 1.7; 95% CI: 1.4‐2.1); at 2 years, the proportion had increased to 11% versus 5% (risk ratio 2.0; 95% CI: 1.7‐2.4); and at 3 years, it had increased to 14% versus 6% (risk ratio 2.2; 95% CI: 1.9‐2.6). CONCLUSIONS: Gastric bypass surgery was associated with increased use of hypnotics and/or sedatives compared with intensive lifestyle modification. John Wiley and Sons Inc. 2017-06-29 2017-08 /pmc/articles/PMC5533175/ /pubmed/28660652 http://dx.doi.org/10.1002/oby.21908 Text en © 2017 The Authors. Obesity published by Wiley Periodicals, Inc. on behalf of The Obesity Society (TOS). This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Original Articles Ng, Winda L. Peeters, Anna Näslund, Ingmar Ottosson, Johan Johansson, Kari Marcus, Claude Shaw, Jonathan E. Bruze, Gustaf Sundström, Johan Neovius, Martin Change in Use of Sleep Medications After Gastric Bypass Surgery or Intensive Lifestyle Treatment in Adults with Obesity |
title | Change in Use of Sleep Medications After Gastric Bypass Surgery or Intensive Lifestyle Treatment in Adults with Obesity |
title_full | Change in Use of Sleep Medications After Gastric Bypass Surgery or Intensive Lifestyle Treatment in Adults with Obesity |
title_fullStr | Change in Use of Sleep Medications After Gastric Bypass Surgery or Intensive Lifestyle Treatment in Adults with Obesity |
title_full_unstemmed | Change in Use of Sleep Medications After Gastric Bypass Surgery or Intensive Lifestyle Treatment in Adults with Obesity |
title_short | Change in Use of Sleep Medications After Gastric Bypass Surgery or Intensive Lifestyle Treatment in Adults with Obesity |
title_sort | change in use of sleep medications after gastric bypass surgery or intensive lifestyle treatment in adults with obesity |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533175/ https://www.ncbi.nlm.nih.gov/pubmed/28660652 http://dx.doi.org/10.1002/oby.21908 |
work_keys_str_mv | AT ngwindal changeinuseofsleepmedicationsaftergastricbypasssurgeryorintensivelifestyletreatmentinadultswithobesity AT peetersanna changeinuseofsleepmedicationsaftergastricbypasssurgeryorintensivelifestyletreatmentinadultswithobesity AT naslundingmar changeinuseofsleepmedicationsaftergastricbypasssurgeryorintensivelifestyletreatmentinadultswithobesity AT ottossonjohan changeinuseofsleepmedicationsaftergastricbypasssurgeryorintensivelifestyletreatmentinadultswithobesity AT johanssonkari changeinuseofsleepmedicationsaftergastricbypasssurgeryorintensivelifestyletreatmentinadultswithobesity AT marcusclaude changeinuseofsleepmedicationsaftergastricbypasssurgeryorintensivelifestyletreatmentinadultswithobesity AT shawjonathane changeinuseofsleepmedicationsaftergastricbypasssurgeryorintensivelifestyletreatmentinadultswithobesity AT bruzegustaf changeinuseofsleepmedicationsaftergastricbypasssurgeryorintensivelifestyletreatmentinadultswithobesity AT sundstromjohan changeinuseofsleepmedicationsaftergastricbypasssurgeryorintensivelifestyletreatmentinadultswithobesity AT neoviusmartin changeinuseofsleepmedicationsaftergastricbypasssurgeryorintensivelifestyletreatmentinadultswithobesity |