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Change in Use of Sleep Medications After Gastric Bypass Surgery or Intensive Lifestyle Treatment in Adults with Obesity

OBJECTIVE: To examine the change in use of hypnotics and/or sedatives after gastric bypass surgery or intensive lifestyle modification in adults with obesity. METHODS: Adults with obesity who underwent gastric bypass surgery or initiated intensive lifestyle modification between 2007 and 2012 were id...

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Autores principales: Ng, Winda L., Peeters, Anna, Näslund, Ingmar, Ottosson, Johan, Johansson, Kari, Marcus, Claude, Shaw, Jonathan E., Bruze, Gustaf, Sundström, Johan, Neovius, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533175/
https://www.ncbi.nlm.nih.gov/pubmed/28660652
http://dx.doi.org/10.1002/oby.21908
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author Ng, Winda L.
Peeters, Anna
Näslund, Ingmar
Ottosson, Johan
Johansson, Kari
Marcus, Claude
Shaw, Jonathan E.
Bruze, Gustaf
Sundström, Johan
Neovius, Martin
author_facet Ng, Winda L.
Peeters, Anna
Näslund, Ingmar
Ottosson, Johan
Johansson, Kari
Marcus, Claude
Shaw, Jonathan E.
Bruze, Gustaf
Sundström, Johan
Neovius, Martin
author_sort Ng, Winda L.
collection PubMed
description OBJECTIVE: To examine the change in use of hypnotics and/or sedatives after gastric bypass surgery or intensive lifestyle modification in adults with obesity. METHODS: Adults with obesity who underwent gastric bypass surgery or initiated intensive lifestyle modification between 2007 and 2012 were identified through the Scandinavian Obesity Surgery Registry and a Swedish commercial weight loss database. The two cohorts were matched on BMI, age, sex, education, history of hypnotics and/or sedatives use, and treatment year (surgery n = 20,626; lifestyle n = 11,973; 77% women, mean age 41 years, mean BMI 41 kg/m(2)). The proportion of participants with filled hypnotics and/or sedatives prescriptions was compared yearly for 3 years. RESULTS: In the matched treatment cohorts, 4% had filled prescriptions for hypnotics and/or sedatives during the year before treatment. At 1 year follow‐up, following an average weight loss of 37 kg and 18 kg in the surgery and intensive lifestyle cohorts, respectively, this proportion had increased to 7% in the surgery cohort but remained at 4% in the intensive lifestyle cohort (risk ratio 1.7; 95% CI: 1.4‐2.1); at 2 years, the proportion had increased to 11% versus 5% (risk ratio 2.0; 95% CI: 1.7‐2.4); and at 3 years, it had increased to 14% versus 6% (risk ratio 2.2; 95% CI: 1.9‐2.6). CONCLUSIONS: Gastric bypass surgery was associated with increased use of hypnotics and/or sedatives compared with intensive lifestyle modification.
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spelling pubmed-55331752017-09-18 Change in Use of Sleep Medications After Gastric Bypass Surgery or Intensive Lifestyle Treatment in Adults with Obesity Ng, Winda L. Peeters, Anna Näslund, Ingmar Ottosson, Johan Johansson, Kari Marcus, Claude Shaw, Jonathan E. Bruze, Gustaf Sundström, Johan Neovius, Martin Obesity (Silver Spring) Original Articles OBJECTIVE: To examine the change in use of hypnotics and/or sedatives after gastric bypass surgery or intensive lifestyle modification in adults with obesity. METHODS: Adults with obesity who underwent gastric bypass surgery or initiated intensive lifestyle modification between 2007 and 2012 were identified through the Scandinavian Obesity Surgery Registry and a Swedish commercial weight loss database. The two cohorts were matched on BMI, age, sex, education, history of hypnotics and/or sedatives use, and treatment year (surgery n = 20,626; lifestyle n = 11,973; 77% women, mean age 41 years, mean BMI 41 kg/m(2)). The proportion of participants with filled hypnotics and/or sedatives prescriptions was compared yearly for 3 years. RESULTS: In the matched treatment cohorts, 4% had filled prescriptions for hypnotics and/or sedatives during the year before treatment. At 1 year follow‐up, following an average weight loss of 37 kg and 18 kg in the surgery and intensive lifestyle cohorts, respectively, this proportion had increased to 7% in the surgery cohort but remained at 4% in the intensive lifestyle cohort (risk ratio 1.7; 95% CI: 1.4‐2.1); at 2 years, the proportion had increased to 11% versus 5% (risk ratio 2.0; 95% CI: 1.7‐2.4); and at 3 years, it had increased to 14% versus 6% (risk ratio 2.2; 95% CI: 1.9‐2.6). CONCLUSIONS: Gastric bypass surgery was associated with increased use of hypnotics and/or sedatives compared with intensive lifestyle modification. John Wiley and Sons Inc. 2017-06-29 2017-08 /pmc/articles/PMC5533175/ /pubmed/28660652 http://dx.doi.org/10.1002/oby.21908 Text en © 2017 The Authors. Obesity published by Wiley Periodicals, Inc. on behalf of The Obesity Society (TOS). This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Ng, Winda L.
Peeters, Anna
Näslund, Ingmar
Ottosson, Johan
Johansson, Kari
Marcus, Claude
Shaw, Jonathan E.
Bruze, Gustaf
Sundström, Johan
Neovius, Martin
Change in Use of Sleep Medications After Gastric Bypass Surgery or Intensive Lifestyle Treatment in Adults with Obesity
title Change in Use of Sleep Medications After Gastric Bypass Surgery or Intensive Lifestyle Treatment in Adults with Obesity
title_full Change in Use of Sleep Medications After Gastric Bypass Surgery or Intensive Lifestyle Treatment in Adults with Obesity
title_fullStr Change in Use of Sleep Medications After Gastric Bypass Surgery or Intensive Lifestyle Treatment in Adults with Obesity
title_full_unstemmed Change in Use of Sleep Medications After Gastric Bypass Surgery or Intensive Lifestyle Treatment in Adults with Obesity
title_short Change in Use of Sleep Medications After Gastric Bypass Surgery or Intensive Lifestyle Treatment in Adults with Obesity
title_sort change in use of sleep medications after gastric bypass surgery or intensive lifestyle treatment in adults with obesity
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533175/
https://www.ncbi.nlm.nih.gov/pubmed/28660652
http://dx.doi.org/10.1002/oby.21908
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