The interplay between genetic background and sexual dimorphism of doxorubicin-induced cardiotoxicity

BACKGROUND: Doxorubicin (DOX) is a very effective anticancer medication that is commonly used to treat hematological malignancies and solid tumors. Nevertheless, DOX is known to have cardiotoxic effects that may lead to cardiac dysfunction and failure. In experimental studies, female animals have be...

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Detalles Bibliográficos
Autores principales: Zordoky, Beshay N., Radin, M. Judith, Heller, Lois, Tobias, Anthony, Matise, Ilze, Apple, Fred S., McCune, Sylvia A., Sharkey, Leslie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533296/
https://www.ncbi.nlm.nih.gov/pubmed/28758028
http://dx.doi.org/10.1186/s40959-016-0013-3

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