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An increase in immature β-cells lacking Glut2 precedes the expansion of β-cell mass in the pregnant mouse

A compensatory increase in β-cell mass occurs during pregnancy to counter the associated insulin resistance, and a failure in adaptation is thought to contribute to gestational diabetes. Insulin-expressing but glucose-transporter-2-low (Ins(+)Glut2(LO)) progenitor cells are present in mouse and huma...

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Detalles Bibliográficos
Autores principales:	Beamish, Christine A., Zhang, Linhao, Szlapinski, Sandra K., Strutt, Brenda J., Hill, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533342/ https://www.ncbi.nlm.nih.gov/pubmed/28753672 http://dx.doi.org/10.1371/journal.pone.0182256

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