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Tex19.1 promotes Spo11-dependent meiotic recombination in mouse spermatocytes
Meiosis relies on the SPO11 endonuclease to generate the recombinogenic DNA double strand breaks (DSBs) required for homologous chromosome synapsis and segregation. The number of meiotic DSBs needs to be sufficient to allow chromosomes to search for and find their homologs, but not excessive to the...
Autores principales: | Crichton, James H., Playfoot, Christopher J., MacLennan, Marie, Read, David, Cooke, Howard J., Adams, Ian R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533463/ https://www.ncbi.nlm.nih.gov/pubmed/28708824 http://dx.doi.org/10.1371/journal.pgen.1006904 |
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