The modulation of enzyme indoleamine 2,3-dioxygenase from dendritic cells for the treatment of type 1 diabetes mellitus

Diabetes mellitus type 1 (DM1) is an autoimmune disease in which β-cells of the pancreas islet are destroyed by T lymphocytes. Specific T cells are activated by antigen-presenting cells, mainly dendritic cells (DCs). It is already known that the regulation of tryptophan pathway in DC can be a mechan...

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Detalles Bibliográficos
Autores principales: Abram, Débora Moitinho, Fernandes, Luis Gustavo Romani, Ramos Filho, Antônio Celso Saragossa, Simioni, Patrícia Ucelli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533566/
https://www.ncbi.nlm.nih.gov/pubmed/28769554
http://dx.doi.org/10.2147/DDDT.S135367

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