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Oriented antibody immobilization to polystyrene macrocarriers for immunoassay modified with hydrazide derivatives of poly(meth)acrylic acid

BACKGROUND: Hydrophobic polystyrene is the most common material for solid phase immunoassay. Proteins are immobilized on polystyrene by passive adsorption, which often causes considerable denaturation. Biological macromolecules were found to better retain their functional activity when immobilized o...

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Detalles Bibliográficos
Autores principales: Shmanai, Vadim V, Nikolayeva, Tamara A, Vinokurova, Ludmila G, Litoshka, Anatoli A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC55337/
https://www.ncbi.nlm.nih.gov/pubmed/11545680
http://dx.doi.org/10.1186/1472-6750-1-4