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Robust and accurate digital measurement for HER2 amplification in HER2 equivocal breast cancer diagnosis

Currently, there are no recommended alternative assays for HER2 cases deemed equivocal by immunohistochemistry and fluorescent in situ hybridization. Digital PCR (ddPCR), a highly accurate method to determine DNA copy number, could be a robust alternative for clinical HER2 diagnostics. HER2 and CEP1...

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Detalles Bibliográficos
Autores principales: Wang, Yuefeng, Tsang, Julia Y. S., Cui, Yongmei, Cui, Ji, Lin, Ying, Zhao, Songli, Law, Patrick T. W., Cheung, Sai Yin, Ng, Enders K. O., Tse, Gary M. K., Ke, Zunfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533703/
https://www.ncbi.nlm.nih.gov/pubmed/28754904
http://dx.doi.org/10.1038/s41598-017-07176-x

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