Cargando…

Dynamic scaffolds for neuronal signaling: in silico analysis of the TANC protein family

The emergence of genes implicated across multiple comorbid neurologic disorders allows to identify shared underlying molecular pathways. Recently, investigation of patients with diverse neurologic disorders found TANC1 and TANC2 as possible candidate disease genes. While the TANC proteins have been...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gasparini, Alessandra, Tosatto, Silvio C. E., Murgia, Alessandra, Leonardi, Emanuela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533708/ https://www.ncbi.nlm.nih.gov/pubmed/28754924 http://dx.doi.org/10.1038/s41598-017-05748-5

Ejemplares similares

Post-synaptic scaffold protein TANC2 in psychiatric and somatic disease risk
por: Garrett, Lillian, et al.
Publicado: (2022)

PanViTa: Pan Virulence and resisTance analysis
por: Rodrigues, Diego Lucas Neres, et al.
Publicado: (2023)

Trzy tance polskie : Polonez, Krakowiak, Oberek : z opery Cud mniemany, czyli, Krakowiacy i Górale /
por: Stefani, Jan, 1746-1829
Publicado: (1953)

Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders
por: Guo, Hui, et al.
Publicado: (2019)

Tanc2-mediated mTOR inhibition balances mTORC1/2 signaling in the developing mouse brain and human neurons
por: Kim, Sun-Gyun, et al.
Publicado: (2021)

Author Correction: Tanc2-mediated mTOR inhibition balances mTORC1/2 signaling in the developing mouse brain and human neurons
por: Kim, Sun-Gyun, et al.
Publicado: (2022)

Preface: Regulation and Control of Efflux Pumps that Mediate Multi-drug Resis-tance of Pathogenic Bacteria
por: Amaral, Leonard
Publicado: (2013)

INGA: protein function prediction combining interaction networks, domain assignments and sequence similarity
por: Piovesan, Damiano, et al.
Publicado: (2015)

A Computational Model of the LGI1 Protein Suggests a Common Binding Site for ADAM Proteins
por: Leonardi, Emanuela, et al.
Publicado: (2011)

TANC1 methylation as a novel biomarker for the diagnosis of patients with anti-tuberculosis drug-induced liver injury
por: Wu, Dongxue, et al.
Publicado: (2021)

Truncating mutation in TANC2 in a Chinese boy associated with Lennox-Gastaut syndrome: a case report
por: Tian, Yang, et al.
Publicado: (2021)

VHLdb: A database of von Hippel-Lindau protein interactors and mutations
por: Tabaro, Francesco, et al.
Publicado: (2016)

In silico Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases
por: Iglesias, Valentin, et al.
Publicado: (2019)

Active Methamphetamine Use is Associated with Transmitted Drug Resis-tance to Non-Nucleoside Reverse Transcriptase Inhibitors in Individuals with HIV Infection of Unknown Duration
por: Cachay, Edward R, et al.
Publicado: (2007)

Studying Interactions by Molecular Dynamics Simulations at High Concentration
por: Fogolari, Federico, et al.
Publicado: (2012)

BOOGIE: Predicting Blood Groups from High Throughput Sequencing Data
por: Giollo, Manuel, et al.
Publicado: (2015)

Secretion-Positive LGI1 Mutations Linked to Lateral Temporal Epilepsy Impair Binding to ADAM22 and ADAM23 Receptors
por: Dazzo, Emanuela, et al.
Publicado: (2016)

Chasing coevolutionary signals in intrinsically disordered proteins complexes
por: Iserte, Javier A., et al.
Publicado: (2020)

Where differences resemble: sequence-feature analysis in curated databases of intrinsically disordered proteins
por: Necci, Marco, et al.
Publicado: (2018)

Computational analysis of prolyl hydroxylase domain-containing protein 2 (PHD2) mutations promoting polycythemia insurgence in humans
por: Minervini, Giovanni, et al.
Publicado: (2016)

Analysis and consensus of currently available intrinsic protein disorder annotation sources in the MobiDB database
por: Di Domenico, Tomás, et al.
Publicado: (2013)

In silico prediction of blood cholesterol levels from genotype data
por: Reggiani, Francesco, et al.
Publicado: (2020)

TAP score: torsion angle propensity normalization applied to local protein structure evaluation
por: Tosatto, Silvio CE, et al.
Publicado: (2007)

Regulation of Signal Duration and the Statistical Dynamics of Kinase Activation by Scaffold Proteins
por: Locasale, Jason W., et al.
Publicado: (2008)

The surprising dynamics of scaffolding proteins
por: Garbett, Damien, et al.
Publicado: (2014)

INGA 2.0: improving protein function prediction for the dark proteome
por: Piovesan, Damiano, et al.
Publicado: (2019)

Regulation of KIF1A-Driven Dense Core Vesicle Transport: Ca(2+)/CaM Controls DCV Binding and Liprin-α/TANC2 Recruits DCVs to Postsynaptic Sites
por: Stucchi, Riccardo, et al.
Publicado: (2018)

Scaffolding proteins in G-protein signaling
por: Andreeva, Alexandra V, et al.
Publicado: (2007)

In silico work flow for scaffold hopping in Leishmania
por: Waugh, Barnali, et al.
Publicado: (2014)

How neurons migrate: a dynamic in-silico model of neuronal migration in the developing cortex
por: Setty, Yaki, et al.
Publicado: (2011)

2mit, an Intronic Gene of Drosophila melanogaster timeless2, Is Involved in Behavioral Plasticity
por: Baggio, Francesca, et al.
Publicado: (2013)

Critical assessment of protein intrinsic disorder prediction
por: Necci, Marco, et al.
Publicado: (2021)

Pfam: The protein families database in 2021
por: Mistry, Jaina, et al.
Publicado: (2020)

Identification of SETBP1 Mutations by Gene Panel Sequencing in Individuals With Intellectual Disability or With “Developmental and Epileptic Encephalopathy”
por: Leonardi, Emanuela, et al.
Publicado: (2020)

Impact of the COVID-19 Italian Lockdown on the Physiological and Psychological Well-Being of Children with Fragile X Syndrome and Their Families
por: Di Giorgio, Elisa, et al.
Publicado: (2021)

SODA: prediction of protein solubility from disorder and aggregation propensity
por: Paladin, Lisanna, et al.
Publicado: (2017)

QMEANclust: estimation of protein model quality by combining a composite scoring function with structural density information
por: Benkert, Pascal, et al.
Publicado: (2009)

Neuronal cotransport of glycine receptor and the scaffold protein gephyrin
por: Maas, Christoph, et al.
Publicado: (2006)

In Silico Structural, Functional, and Phylogenetic Analysis of Cytochrome (CYPD) Protein Family
por: Ahmad, Hafiz Ishfaq, et al.
Publicado: (2021)

Could the Heat Shock Proteins 70 Family Members Exacerbate the Immune Response in Multiple Sclerosis? An in Silico Study
por: Chiricosta, Luigi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_i6miraclokcptakhtmp7drei76