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Reciprocal regulation of TLR2-mediated IFN-β production by SHP2 and Gsk3β

Toll-like receptor 2 (TLR2) mediates the innate immune response to bacterial lipopeptides and peptidoglycans by stimulating the production of inflammatory cytokines. However, the mechanisms by which TLR2 signaling regulates type I interferon (IFN)-β production are poorly understood. Here, we identif...

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Detalles Bibliográficos
Autores principales: Park, Jin Hee, Ko, Ryeojin, Lee, Soo Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533723/
https://www.ncbi.nlm.nih.gov/pubmed/28754897
http://dx.doi.org/10.1038/s41598-017-07316-3

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