Salt Bridge Formation between the I-BAR Domain and Lipids Increases Lipid Density and Membrane Curvature

The BAR domain superfamily proteins sense or induce curvature in membranes. The inverse-BAR domain (I-BAR) is a BAR domain that forms a straight “zeppelin-shaped” dimer. The mechanisms by which IRSp53 I-BAR binds to and deforms a lipid membrane are investigated here by all-atom molecular dynamics si...

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Detalles Bibliográficos
Autores principales: Takemura, Kazuhiro, Hanawa-Suetsugu, Kyoko, Suetsugu, Shiro, Kitao, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533756/
https://www.ncbi.nlm.nih.gov/pubmed/28754893
http://dx.doi.org/10.1038/s41598-017-06334-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533756/
https://www.ncbi.nlm.nih.gov/pubmed/28754893
http://dx.doi.org/10.1038/s41598-017-06334-5

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