Neurometabolic and electrophysiological changes during cortical spreading depolarization: multimodal approach based on a lactate-glucose dual microbiosensor arrays

Spreading depolarization (SD) is a slow propagating wave of strong depolarization of neural cells, implicated in several neuropathological conditions. The breakdown of brain homeostasis promotes significant hemodynamic and metabolic alterations, which impacts on neuronal function. In this work we ai...

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Detalles Bibliográficos
Autores principales: Lourenço, Cátia F., Ledo, Ana, Gerhardt, Greg A., Laranjinha, João, Barbosa, Rui M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533760/
https://www.ncbi.nlm.nih.gov/pubmed/28754993
http://dx.doi.org/10.1038/s41598-017-07119-6